Mankind, full of egoism and idolatry, refuses to hear wisdom, as she is crying out for all to hear and see. What follows is the result of rejecting the wisdom that is offered.
24 Because I have called, and ye refused; I have stretched out my hand, and no man regarded;
25 But ye have set at nought all my counsel, and would none of my reproof:
26 I also will laugh at your calamity; I will mock when your fear cometh; 27 When your fear cometh as desolation, and your destruction cometh as a whirlwind; when distress and anguish cometh upon you.
Since true wisdom comes only from God, the Bible says that following the wisdom of the world is to invite calamity. Our nation has invited destruction. Just look at this quote from famous evangelist, Billy Sunday(1862-1935):
“Rivers of America will run with blood filled to their banks before we will submit to them taking the Bible out of our schools.”
How quickly America submitted. In 1962 and 1963, respectively, prayer and the Word of God were removed from our public schools. Read more here.
As the Proverb comes to an end, Wisdom states that she will not answer when called upon after being ignored and cast aside.
27 When your fear cometh as desolation, and your destruction cometh as a whirlwind; when distress and anguish cometh upon you. 28 Then shall they call upon Me, but I will not answer; they shall seek Me early, but they shall not find Me:
29 For that they hated knowledge, and did not choose the fear of the Lord:
30 They would none of My counsel: they despised all My reproof.
31 Therefore shall they eat of the fruit of their own way, and be filled with their own devices. 32 For the turning away of the simple shall slay them, and the prosperity of fools shall destroy them.
Following the prosperity of fools??? Ridiculous fashion trends, extravagant lifestyles, personality cults, excessive consumerism, idolization of sports figures and celebrities. . .
But whoso hearkeneth unto Me shall dwell safely, and shall be quiet from fear of evil.
The Vine Vigil 
